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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
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08.01.03  Expand sub section  Antimetabolites
Cytotoxic Drug Azacitidine Injection 100mg (Vidaza)
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Link  NICE TA399: Azacitidine for treating acute myeloid leukaemia with more than 30% bone marrow blasts (NOT recommended)
   
Cytotoxic Drug Capecitabine Tablets 150mg and 500mg (Xeloda)
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Formulary
Red
 
   
Cytotoxic Drug Cladribine
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Formulary Concentrate for IV Infusion 10mg/10ml
Injection 10mg/5ml 
   
Clofarabine (Evoltra)
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Restricted Drug Restricted Clofarabine is to be used in trials only. 
   
Cytotoxic Drug Cytarabine
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Formulary Injection: 100mg/5ml, 100mg/ml, 1g/10ml, 2g/20ml. 
   
Cytotoxic Drug Fludarabine Phosphate (Fludara)
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Formulary Tablets 10mg
Injection 50mg 
   
Cytotoxic Drug Fluorouracil
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Formulary Injection: 250mg/10ml, 500mg/10ml and 5g/100ml
Prefilled Syringe: 200mg/4ml, 500mg/10ml, 550mg/11ml, 600mg/12ml, 650mg/13ml and 750mg/15ml. 
   
Cytotoxic Drug Gemcitabine Injection 200mg and 1g (Gemzar)
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Link  NICE TA389: Topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for treating recurrent ovarian cancer
   
Cytotoxic Drug Mercaptopurine Tablets  (Puri-Nethol)
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Formulary Tablets: 50mg and 10mg 
   
Cytotoxic Drug Methotrexate
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Formulary
Red
Injection: 5mg/2ml, 50mg/2ml, 500mg/20ml, 1g/10ml and 5g/50ml.

Tablets: 2.5mg

For malignancy only. For other indications, see relevant chapters
 
   
Cytotoxic Drug Pemetrexed Injection 100mg and 500mg (Alimta)
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Link  NICE TA309: Lung cancer (non small cell, non squamous) - pemetrexed
Link  NICE TA402: Pemetrexed maintenance treatment for non-squamous non-small-cell lung cancer after pemetrexed and cisplatin
   
Tioguanine Tablets 40mg (Lanvis)
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 ....
 Non Formulary Items
Cladribine  (Litak)

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Non Formulary
 
Cytarabine  (DepoCyte®)

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Non Formulary
 
Fluorouracil  (Efudix)

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Non Formulary
 
Raltitrexed  (Tomudex®)

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Non Formulary
 
Cytotoxic Drug  Tegafur with Uracil  (Uftoral)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
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Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber 1

"Amber 1" - These are medicines that require significant monitoring and the decision to treat with an AMBER medicine should be made by specialists only  

Amber 2

"Amber 2" - These are medicines that require little or no monitoring by the GP, but should only be prescribed in general practice after they have been recommended following specialist referral.  

Red

"Red" - Secondary care only  

RedRed

"Double Red" - NOT recommended for prescribing in either primary or secondary care  

Grey

Traffic light status to be confirmed  

Green

May be prescribed in primary and secondary care  

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