| Formulary Chapter 5: Infections - Full Chapter
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| Chapter Links... |
 Antibiotic Policy (KGH Only) |
| Empirical antibiotic guidelines summary (KGH only) |
| Details... |
| 05.01 |
Antibacterial drugs |
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| 05.01 |
Table 1. Summary of antibacterial therapy |
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| 05.01 |
Table 2. Summary of antibacterial prophylaxis |
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| 05.01.01.01 |
Benzylpenicillin and phenoxymethylpenicillin |
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Benzylpenicillin Injection 600mg (Crystapen®)
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Formulary
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CAUTION: loading dose for intrapartum prophylaxis against group B streptococcal infection - see SPC, BNF
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Phenoxymethylpenicillin
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Formulary
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Tablets 250mg
Liquid: 125mg/5ml and 250mg/5ml
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| 05.01.01.02 |
Penicillinase-resistant penicillins |
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Flucloxacillin
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Formulary
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Capsules: 250mg and 500mg
Liquid: 125mg/5ml and 250mg/5ml
Injection: 250mg, 500mg and 1g
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Temocillin (Negaban®)
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Formulary
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1g powder for reconstitution for intramuscular or intravenous injection or intravenous infusion
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| 05.01.01.03 |
Broad-spectrum penicillins |
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Amoxicillin
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Formulary
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Capsules: 250mg and 500mg
Liquid: 125mg/5ml and 250mg/5ml
Injection: 250mg and 500mg
Sachets 3g
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Ampicillin Injection 500mg
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 Restricted
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Permitted for specific indications only according to trust guidelines or on microbiology advice.
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Co-Amoxiclav
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Formulary
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Use of this antibiotic is associated with a high risk of Clostridium difficile infection.
Tablets: 375mg and 625mg
Liquid: 125/31 and 250/62
Injection: 600mg and 1.2g
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| 05.01.01.04 |
Antipseudomonal penicillins |
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Piperacillin and Tazobactam Injection
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Formulary
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Injection 2.25g and 4.5g
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Ticarcillin Injection 3.2g (Timentin®)
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Formulary
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Pivmecillinam Hydrochloride 200mg tablets (Selexid®)
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Restricted
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Use only following Microbiology recommendation based on sensitivities
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| 05.01.02 |
Cephalosporins, carbapenems and other beta-lactums |
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| 05.01.02.01 |
Cephalosporins |
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Cefalexin
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Formulary
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The use of this antibiotic is associated with a high risk of Clostridium difficile infection.
Capsules 250mg
Suspension: 125mg/5ml and 250mg/5ml
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Cefotaxime Injection
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Restricted
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The use of cefotaxime is restricted to SCBU only.
The use of this antibiotic is associated with a high risk of Clostridium difficile infection.
Injection: 500mg, 1g and 2g
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Ceftazidime Injection
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Formulary
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The use of this antibiotic is associated with a high risk of Clostridium difficile infection.
Injection: 500mg and 1g
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Ceftazidime with avibactam 2g/0.5gpowder for concentrate for solution for infusion (Zavicefta)
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Restricted
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Available following recommendation from Microbiology
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Ceftriaxone Injection
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Formulary
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The use of this antibiotic is associated with a high risk of Clostridium difficile infection.
Injection: 250mg, 1g and 2g.
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Cefuroxime Injection
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Formulary
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The use of this antibiotic is associated with a high risk of Clostridium difficile infection.
Injection: 250mg, 750mg and 1.5g
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Ertapenem IV Infusion 1g
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Restricted
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The use of Ertapenem is restricted to ESBL infection or on the advice from microbiology.
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Meropenem Injection 500mg
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Restricted
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The use of Meropenem is permitted for specific indications only.
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| 05.01.02.03 |
Other beta-lactums antibiotics |
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Aztreonam Injection 1g and 2g (Azactam®)
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Formulary
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Doxycycline
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Formulary
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Capsules: 50mg and 100mg
Dispersible Tablets: 100mg
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Oxytetracycline Tablets 250mg
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Formulary
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Demeclocycline Hydrochloride Capsules 150mg
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Restricted
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The use of Demeclocycline is for specific indications only.
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Minocycline capsules 100mg
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Restricted
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100mg capsules available - restricted for use in Oncology only
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| 05.01.03 |
Tigecycline |
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Tigecycline IV Infusion 50mg (Tygacil®)
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Formulary
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Gentamicin Injection
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Formulary
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Injection 80mg/2ml
Paediatric Injection 20mg/2ml
Intrathecal Injection 5mg/ml
CAUTION: for once daily high dose see BNF, BNFC, antibiotic policy
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Neomycin Sulphate Tablets 500mg
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Formulary
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Tobramycin (Bramitob®)
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Restricted
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 NICE TA276: Cystic fibrosis (pseudomonas lung infection) - colistimethate sodium and tobramycin
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Tobramycin (Tobi®)
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Restricted
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NICE TA276: Cystic fibrosis (pseudomonas lung infection) - colistimethate sodium and tobramycin
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Tobramycin Injection 40mg and 80mg
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Restricted
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The use of tobramycin is restricted to paediatrics only.
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Clarithromycin
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Formulary
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Tablets 250mg
Liquid: 125mg/5ml and 250mg/5ml
Injection 500mg
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Erythromycin
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Formulary
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Tablets 250mg
Liquid: 125mg/5ml, 250mg/5ml and 500mg/5ml
Injection 1g
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Azithromycin
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Restricted
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The use of Azithromycin is restricted to specific indications only in accordance with the antibiotic guidelines and for use in paediatrics.
Capsules 250mg
Tablets 500mg
Liquid 200mg/5ml
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Clindamycin
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Restricted
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The use of Clindamycin is restricted to specific indications only in accordance with the hospital antibiotic guidelines.
The use of this antibiotic is associated with a higher risk of Clostridium difficile infection.
Capsules 150mg
Injection 150mg/ml
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| 05.01.07 |
Some other antibacterials |
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Rifaximin tablets 550mg (Targaxan®)
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Restricted
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Initiation by Consultant Gastroenterologists only
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NICE TA337: Rifaximin for preventing episodes of overt hepatic encephalopathy
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| 05.01.07 |
Chloramphenicol |
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Chloramphenicol Injection 1g
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Restricted
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FOSFOMYCIN Sachets 3 g
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Formulary
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Sodium fusidate
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Formulary
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Tablets 250mg
IV Infusion NOW DISCONTINUED (March 2013)
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| 05.01.07 |
Vancomycin and teicoplanin |
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Dalbavancin 500mg injection (Xydalba®)
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Restricted
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For initiation by Micro team only
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Teicoplanin Injection 200mg and 400mg
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Formulary
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CAUTION:for loading dose see SPC, BNF, BNFC, antibiotic policy
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Vancomycin
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Formulary
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Capsules 125mg
Injection 500mg
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Daptomycin (Cubicin®)
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Restricted
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Injection 350mg and 500mg
Available only following recommendation from a Consultant Microbiologist
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| 05.01.07 |
Linezolid |
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Linezolid
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Formulary
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Tablets 600mg
Suspension 100mg/5ml
IV Infusion 600mg/300ml
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| 05.01.07 |
Quinupristin and dalfopristin |
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Colistimethate Sodium 1million unit injection (Colomycin®)
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Restricted
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Injection may be given intravenously or via nebulizer.
Initiation on advice of Microbiology/Respiratory Physician
Colistimethate sodium injection for nebulisation for CF - RED
Nebulised colistimethate sodium in non-CF bronchiectasis – AMBER 2
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Colistimethate Sodium 1,662,500 unit inhalation powder capules (Colobreathe®)
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Restricted
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Not routinely stocked. Ordered on demand for qualifying patients.
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NICE TA276: Cystic fibrosis (pseudomonas lung infection) - colistimethate sodium and tobramycin
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| 05.01.08 |
Sulphonamides and trimethoprim |
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Co-trimoxazole
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Formulary
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Tablets 480mg
Paediatric Oral Suspension 240mg/5ml
Suspension 480mg/5ml
IV Infusion 96mg/ml
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Trimethoprim
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Formulary
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Tablets: 100mg and 200mg
Suspension 50mg/5ml
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| 05.01.09 |
Antituberculosis drugs |
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Ethambutol Hydrochloride Tablets 100mg and 400mg (Ethambutol®)
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Formulary
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400mg/5ml liquid formulation can be orderd on demand
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Isoniazid
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Formulary
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Tablets 100mg
Liquid 50mg/5ml : This is an unlicensed medicine.
Injection 50mg/2ml
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Pyrazinamide Tablets 500mg
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Formulary
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Pyrazinamide is an unlicensed medicine.
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Rifabutin Capsules 150mg (Mycobutin®)
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Formulary
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Rifampicin
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Formulary
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Capsules: 150mg and 300mg
Liquid 100mg/5ml
IV Infusion 600mg
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Rifampicin and Isoniazid Tablets (Rifinah® 300)
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Formulary
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Rifampicin and Isoniazid Tablets (Rifinah® 150)
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Formulary
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Rifampicin, Isoniazid and Pyrazinamide Tablets (Rifater®)
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Formulary
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Streptomycin Sulphate Injection 1g
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Restricted
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The use of streptomycin is restricted. It should only be used on the advice from a respiratory consultant or microbiology.
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| 05.01.10 |
Antileprotic drugs |
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Dapsone Tablets 50mg
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Formulary
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| 05.01.11 |
Metronidazole and tinidazole |
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Metronidazole
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Formulary
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Tablets: 200mg and 400mg
Suspension 200mg/5ml
IV Infusion: 100mg/20ml and 500mg/100ml
Suppositories: 500mg and 1g
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Ciprofloxacin
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Formulary
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The use of this antibiotic is associated with a high risk of Clostridium difficile infection.
Tablets 250mg
IV Infusion: 100mg/50ml, 200mg/100mg and 400mg/200ml.
Suspension 250mg/5ml
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Levofloxacin (Tavanic®)
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Restricted
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The use of this antibiotic is associated with a high risk of Clostridium difficile infection.
Tablets 500mg
IV Infusion 500mg/100ml
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Ofloxacin Tablets 400mg
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Restricted
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The use of ofloxacin is restricted to specific indications only in accordance with the hospital antibiotic guidelines.
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| 05.01.13 |
Urinary-tract infections |
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Trimethoprim
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First Choice
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Tablets: 100mg and 200mg
Suspension 50mg/5ml
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Nitrofurantoin
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Second Choice
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Tablets 50mg
Suspension 25mg/5ml
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| 05.02 |
Treatment of fungal infections |
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| 05.02 |
Drugs used in fungal infections |
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Fluconazole
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Formulary
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Capsules: 50mg, 150mg and 200mg.
IV Infusion: 50mg/25ml and 200mg/100ml
Suspension: 50mg/5ml and 200mg/5ml
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Miconazole Oral Gel 2% (Daktarin®)
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Formulary
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Nystatin Suspension 100,000units/ml (Nystan®)
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Formulary
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Terbinafine Tablets 250mg
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Formulary
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Itraconazole (Sporanox®)
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Restricted
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The use of itraconazole is restricted to haematology only.
Capsules 100mg
Liquid 50mg/5ml
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Amphotericin IV Infusion 50mg (AmBisome®)
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Restricted
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Permitted for specific indications only.
Use outside Haematology requires microbiology approval.
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Caspofungin IV Infusion 50mg and 70mg (Cancidas®)
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Restricted
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Permitted for specific indications only.
Use outside ICU and Haematology require microbiology approval.
CAUTION:for loading dose see BNF, BNFC, SPC
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Posaconazole (Noxafil®)
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Restricted
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Tablets 100mg
Suspension 200mg/5ml
*NOTE The tablets and suspension are not interchangeable. Prescriptions must specify the required formulation (see link)*
The use of posaconazole is restricted to haematology only.
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Drug Safety Update September 2016 - Posaconazole formulations
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Voriconazole (Vfend®)
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Restricted
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The use of voriconazole is restricted to haematology only.
Tablets: 50mg and 200mg
Suspension 200mg/5ml
IV Infusion 200mg
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| 05.02.01 |
Triazole antifungals |
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| 05.02.02 |
Imidazole antifungals |
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| 05.02.03 |
Polyene antifungals |
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| 05.02.04 |
Echinocandin antifungals |
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| 05.02.05 |
Other antifungals |
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| 05.03.01 |
HIV infection |
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HIV Post Exposure Prophylaxis Pack (PEP)
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Restricted
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The pack contains a 7-day supply of:
-Truvada (emtricitabine 200mg/tenofovir disoproxil 245mg)
-Raltegravir 400mg
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EAGA guidance on HIV post-exposure prophylaxis (occupational exposure)
UK National Guideline for the Use of HIV Post-Exposure Prophylaxis Following Sexual Exposure (PEPSE) 2015
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| 05.03.01 |
Nucleoside reverse transcriptase inhibitors |
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Lamivudine (Epivir®)
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Restricted
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Lamivudine is stocked in the emergency cupboard for paediatrics.
Tablets 150mg
Liquid 50mg/5ml
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Lamivudine tablets 100mg (Zeffix®)
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Restricted
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Restricted to Gastroenterology use for Hepatitis B
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Tenofovir Disproxil tablets 245mg (Viread®)
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Restricted
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Available for use in the management of chronic hepatitis B according to NICE criteria.
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NICE TA173: Tenofovir disoproxil for the treatment of chronic hepatitis B
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Zidovudine (Retrovir®)
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Restricted
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Zidovudine is stocked in the emergency cupboard for paediatrics.
Capsules: 100mg and 250mg
Liquid 50mg/5ml
Injection 200mg/20ml
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| 05.03.01 |
Protease inhibitors |
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| 05.03.01 |
Non-nucleoside reverse transcriptase inhibitors |
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Nevirapine (Viramune®)
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Restricted
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Nevirapine is stocked in the emergency cupboard for paediatrics.
Tablets 200mg
Suspension 50mg/5ml
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| 05.03.01 |
Other antiretrovirals |
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| 05.03.01 |
Pharmacokinetic enhancers of antiretrovirals |
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| 05.03.01 |
Combination Products |
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| 05.03.02 |
Herpesvirus infections |
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| 05.03.02.01 |
Herpes simplex and varicella-zoster infection |
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Aciclovir
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Formulary
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Tablets: 200mg, 400mg and 800mg
Dispersible Tablets 800mg
Suspension: 200mg/5ml and 400mg/5ml
IV Infusion: 250mg and 500mg
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Valaciclovir (Valtrex®)
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Restricted
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The use of valaciclovir is restricted to haematology only.
Tablets 500mg
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| 05.03.02.02 |
Cytomegalovirus infection |
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Ganciclovir IV Infusion 500mg (Cymevene®)
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Restricted
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Valganciclovir Tablets 450mg (Valcyte®)
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Restricted
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| 05.03.03 |
Viral hepatitis |
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| 05.03.03.01 |
Chronic hepatitis B |
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| 05.03.03.02 |
Chronic hepatitis C |
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Telaprevir 375mg Tablets (Incivo® 375mg Tablets)
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Restricted
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Ordered on demand for named patients only.
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NICE TA252: Hepatitis C (genotype 1) - telaprevir
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Boceprevir 200mg Capsules (Victrelis® 200mg Capsules)
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Restricted
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Ordered on demand for named patients only.
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NICE TA253:Hepatitis C (genotype 1) - boceprevir
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Daclatasvir 30mg & 60mg tablets (Daklinza®)
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Restricted
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For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy
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NICE TA364: Daclatasvir for treating chronic hepatitis C
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Ledipasvir/sofosbuvir 90/400mg tablets (Harvoni®)
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Restricted
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For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy
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NICE TA363: Ledipasvir–sofosbuvir for treating chronic hepatitis C
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Ombitasvir/paritaprevir/ritonavir 12.5/75/50mg tablets (Viekirax®)
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Restricted
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For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy
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NICE TA365: Ombitasvir–paritaprevir–ritonavir with or without dasabuvir for treating chronic hepatitis C
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Simeprevir 400mg tablets (Olysio®)
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Restricted
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For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy
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NICE TA331: Simeprevir in combination with peginterferon alfa and ribavirin for treating genotypes 1 and 4 chronic hepatitis C
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Sofosbuvir 150mg capsules (Sovaldi®)
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Restricted
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For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy
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NICE TA330: Sofosbuvir for treating chronic hepatitis C
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Sofosbuvir 400mg/velpatasvir 100mg tablets (Epclusa®)
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Restricted
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High Cost Medicine
Red For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy
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NICE TA430: Sofosbuvir–velpatasvir for treating chronic hepatitis C
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Elbasvir 50mg with grazoprevir 100mg tablets (Zepatier®)
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Restricted
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For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy
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NICE TA413: Elbasvir–grazoprevir for treating chronic hepatitis C
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Oseltamivir (Tamiflu®)
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Restricted
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Capsules: 30mg, 45mg and 75mg
Suspension: 30mg/5ml
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Zanamivir Dry Powder for Inhalation 5mg (Relenza®)
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Restricted
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Zanamivir solution for injection or nebulisation
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Restricted
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The use of zanamivir aqueous solution (for nebulised or intravenous use) is unlicensed. No stocks are held on site and must be requested on a named patient basis.
Contact Pharmacy for further information.
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| 05.03.05 |
Respiratory syncytial virus |
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Ribavirin (Rebetol®)
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Restricted
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NICE TA200: Hepatitis C - peginterferon alfa and ribavirin
NICE TA300: Hepatitis C (children and young people) - peginterferon alfa and ribavirin
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Palivizumab Injection 100mg (Synagis®)
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Restricted
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The use of Palivisumab is restricted to paediatrics only for RSV.
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Ribavirin (Copegus®)
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Restricted
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NICE TA200: Hepatitis C - peginterferon alfa and ribavirin
NICE TA300: Hepatitis C (children and young people) - peginterferon alfa and ribavirin
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| 05.04 |
Antiprotozoal drugs |
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| 05.04.01 |
Treatment of malaria |
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| 05.04.01 |
Falciparum malaria (treatment) |
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| 05.04.01 |
Benign malarias (treatment) |
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| 05.04.01 |
Prophylaxis against malaria |
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| 05.04.01 |
Specific recommendations |
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| 05.04.01 |
Artemether with lumefabtrine |
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Chloroquine Tablets 250mg
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Formulary
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Mefloquine Tablets 250mg (Lariam®)
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Formulary
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| 05.04.01 |
Primaquine |
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Proguanil Hydrochloride Tablets 100mg (Paludrine®)
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Formulary
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Pyrimethamine Tablets 25mg (Darprim®)
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Formulary
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Pyrimethamine with Sulfadoxine Tablets (Fansidar®)
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Formulary
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Fansidar tablets are unlicensed.
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Quinine Dihydrochloride Injection 300mg/ml
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Formulary
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This is an unlicensed medicine.
CAUTION: loading dose for treatment of falciparum malaria - see BNF, BNFC
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Quinine Sulphate Tablets 300mg
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Formulary
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Doxycycline
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Formulary
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Capsules: 50mg and 100mg
Dispersible Tablets 100mg
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| 05.04.02 |
Amoebicides |
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Metronidazole
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Formulary
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Tablets 200mg
Suspension 200mg/5ml
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Metronidazole
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Formulary
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Tablets 200mg
Suspension 200mg/5ml
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| 05.04.04 |
Antigiardial drugs |
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Metronidazole
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Formulary
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Tablets 200mg
Suspension 200mg/5ml
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| 05.04.07 |
Drugs for toxoplasmosis |
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| 05.04.08 |
Drugs for pneumocystis pneumonia |
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Co-trimoxazole
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Formulary
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Tablets 480mg
Suspension: 240mg/5ml and 480mg/5ml
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Pentamidine Isetionate Injection 300mg (Pantacarinat®)
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Restricted
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| 05.05.01 |
Drugs for threadworms |
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Mebendazole Tablets 100mg
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Formulary
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| 05.05.03 |
Drugs for tapeworm infections |
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| 05.05.04 |
Drugs for hookworms |
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| 05.05.05 |
Schistosomicides |
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| 05.05.07 |
Drugs for cutaneous larva migrans |
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| 05.05.08 |
Drugs for strongyloidiasis |
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| .... |
| Non Formulary Items |
Abacavir (Ziagen®)
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Non Formulary
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Abacavir and Lamivudine (Kivexa®)
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Non Formulary
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Abacavir and Lamivudine and Zidovudine (Trizivir®)
|
Non Formulary
|
|
|
|
Aciclovir (Zovirax®)
|
Non Formulary
|
|
|
|
Adefovir Dipivoxil (Hepsera®)
|
Non Formulary
|
|
|
|
Albendazole
|
Non Formulary
|
|
|
|
Amantadine Hydrochloride (Lysovir®)
|
Non Formulary
|
|
|
|
Amantadine Hydrochloride (Symmetrel®)
|
Non Formulary
|
|
|
|
Amikacin
|
Non Formulary
|
|
|
|
Amikacin (Amikin®)
|
Non Formulary
|
|
|
|
Amoxicillin (Amoxil®)
|
Non Formulary
|
|
|
|
Amphotericin (Abelcet®)
|
Non Formulary
|
|
|
|
Amphotericin (Amphocil®)
|
Non Formulary
|
|
|
|
Amphotericin (Fungilin®)
|
Non Formulary
|
|
|
|
Amphotericin IV Infusion 50mg (Fungizone®)
|
Non Formulary
|
|
|
|
Ampicillin (Penbritin®)
|
Non Formulary
|
|
|
|
Amprenavir (Agenerase®)
|
Non Formulary
|
|
|
|
Artemether with lumefantrine (Riamet®)
|
Non Formulary
|
|
|
|
Atazanavir (Reyataz®)
|
Non Formulary
|
|
|
|
Atovaquone (Wellvone®)
|
Non Formulary
|
|
|
|
Atovaquone (With Proguanil Hydrochloride)
|
Non Formulary
|
|
|
|
Aztreonam (Cayston®)
|
Non Formulary
|
|
|
|
Capreomycin (Capastat®)
|
Non Formulary
|
|
|
|
Cefixime (Suprax®)
|
Non Formulary
|
|
|
|
Chloramphenicol (Kemicetine®)
|
Non Formulary
|
|
|
|
Chloroquine (Avloclor®)
|
Non Formulary
|
|
|
|
Chloroquine (Malarivon®)
|
Non Formulary
|
|
|
|
Chloroquine (Nivaquine®)
|
Non Formulary
|
|
|
|
Chloroquine (Paludrine® Avloclor)
|
Non Formulary
|
|
|
|
Cidofovir (Vistide®)
|
Non Formulary
|
|
|
|
Ciprofloxacin (Ciproxin®)
|
Non Formulary
|
|
|
|
Clarithromycin
|
Non Formulary
|
|
|
|
Clarithromycin (Clarosip®)
|
Non Formulary
|
|
|
|
Clarithromycin (Klaricid®)
|
Non Formulary
|
|
|
|
Clarithromycin (Klaricid® XL)
|
Non Formulary
|
|
|
|
Clindamycin 150mg Capsules
|
Non Formulary
|
|
|
|
Clindamycin 300mg/2mL Injection
|
Non Formulary
|
|
|
|
Clofazimine
|
Non Formulary
|
|
|
|
Co-Amoxiclav (Augmentin®)
|
Non Formulary
|
|
|
|
Co-Amoxiclav (Augmentin-Duo®)
|
Non Formulary
|
|
|
|
Co-Fluampicil
|
Non Formulary
|
|
|
|
Colistimethate Sodium 1 million International Units Powder for Nebuliser Solution (Promixin®)
|
Non Formulary
|
Colistimethate sodium powder for nebulizer solution for CF (Promixin) (AMBER 2 for patients initiated pre April 2014) |
|
|
Co-trimoxazole (Septrin®)
|
Non Formulary
|
|
|
|
Cycloserine
|
Non Formulary
|
|
|
|
Darunavir (Prezista®)
|
Non Formulary
|
|
|
|
Didanosine (Videx®)
|
Non Formulary
|
|
|
|
Diloxanide Furoate (Diloxanide®)
|
Non Formulary
|
|
|
|
Doxycycline (Efracea® MR)
|
Non Formulary
|
|
|
|
Doxycycline (Vibramycin®)
|
Non Formulary
|
|
|
|
Doxycycline (Vibramycin-D®)
|
Non Formulary
|
|
|
|
Efavirenz (Sustiva®)
|
Non Formulary
|
|
|
|
Emtricitabine (Emtriva®)
|
Non Formulary
|
|
|
|
Enfuvirtide (Fuzeon®)
|
Non Formulary
|
|
|
|
Entecavir (Baraclude®)
|
Non Formulary
|
|
|
|
Erythromycin (Erymax®)
|
Non Formulary
|
|
|
|
Erythromycin (Erythrocin®)
|
Non Formulary
|
|
|
|
Erythromycin (Erythromycin Ethyl Succinate)
|
Non Formulary
|
|
|
|
Erythromycin (Erythromycin Lactobionate)
|
Non Formulary
|
|
|
|
Erythromycin (Erythroped®)
|
Non Formulary
|
|
|
|
Erythromycin (Erythroped® A)
|
Non Formulary
|
|
|
|
Etravirine (Intelence®)
|
Non Formulary
|
|
|
|
Famciclovir (Famvir®)
|
Non Formulary
|
|
|
|
Flucloxacillin (Floxapen®)
|
Non Formulary
|
|
|
|
Fluconazole (Diflucan®)
|
Non Formulary
|
|
|
|
Flucytosine (Ancotil®)
|
Non Formulary
|
|
|
|
Fosamprenavir (Telzir®)
|
Non Formulary
|
|
|
|
Foscarnet Sodium (Foscavir®)
|
Non Formulary
|
|
|
|
Gentamicin (Cidomycin®)
|
Non Formulary
|
|
|
|
Gentamicin (Genticin®)
|
Non Formulary
|
|
|
|
Gentamicin (Isotonic Gentamicin Injection)
|
Non Formulary
|
|
|
|
Glecaprevir with pibrentasvir 100mg/40mg tablets (Maviret®)
|
Non Formulary
|
For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy |
NICE TA499: Glecaprevir–pibrentasvir for treating chronic hepatitis C
|
Griseofulvin
|
Non Formulary
|
|
|
|
Griseofulvin (Fulsovin®)
|
Non Formulary
|
|
|
|
Indinavir (Crixivan®)
|
Non Formulary
|
|
|
|
Inosine Pranobex (Imunovir®)
|
Non Formulary
|
|
|
|
Ketoconazole (Nizoral®)
|
Non Formulary
|
|
|
|
Letermovir (Prevymis®)
|
Non Formulary
|
Relevant service not provided at KGH |
NICE TA591: Letermovir for preventing cytomegalovirus disease after a stem cell transplant
|
Linezolid (Zyvox®)
|
Non Formulary
|
|
|
|
Lopinavir and Ritonavir (Kaletra®)
|
Non Formulary
|
|
|
|
Lymecycline (Tetralysal® 300)
|
Non Formulary
|
|
|
|
Mebendazole (Vermox®)
|
Non Formulary
|
|
|
|
Mepacrine Hydrochloride
|
Non Formulary
|
|
|
|
Methenamine Hippurate (Hiprex®)
|
Non Formulary
|
|
|
|
Metronidazole (Flagyl®)
|
Non Formulary
|
|
|
|
Metronidazole (Flagyl® S)
|
Non Formulary
|
|
|
|
Metronidazole (Metrolyl®)
|
Non Formulary
|
|
|
|
Minocycline (Acnamino® MR)
|
Non Formulary
|
|
|
|
Minocycline (Minocin® MR)
|
Non Formulary
|
|
|
|
Minocycline (Sebomin® MR)
|
Non Formulary
|
|
|
|
Moxifloxacin (Avelox(R))
|
Non Formulary
|
|
|
|
Moxifloxacin (Avelox®)
|
Non Formulary
|
|
|
|
Nalidixic Acid (Uriben®)
|
Non Formulary
|
|
|
|
Nelfinavir (Viracept®)
|
Non Formulary
|
|
|
|
Netilmicin (Netillin®)
|
Non Formulary
|
|
|
|
Nitrofurantoin (Furadantin®)
|
Non Formulary
|
|
|
|
Nitrofurantoin (Macrobid®)
|
Non Formulary
|
|
|
|
Nitrofurantoin (Macrodantin®)
|
Non Formulary
|
|
|
|
Norfloxacin
|
Non Formulary
|
|
|
|
Norfloxacin (Utinor®)
|
Non Formulary
|
|
|
|
Ofloxacin (Tarivid®)
|
Non Formulary
|
|
|
|
Piperazine (Piperazine® Citrate)
|
Non Formulary
|
|
|
|
Piperazine (with Sennosides)
|
Non Formulary
|
|
|
|
Primaquine
|
Non Formulary
|
|
|
|
Proguanil Hydrochloride (With Chloroquine)
|
Non Formulary
|
|
|
|
Proguanil Hydrochloride with Atovaquone (Malarone® Raediatric)
|
Non Formulary
|
|
|
|
Proguanil Hydrochloride with Atovaquone (Malarone®)
|
Non Formulary
|
|
|
|
Prothionamide
|
Non Formulary
|
|
|
|
Pyrimethamine and Dapsone
|
Non Formulary
|
|
|
|
Quinupristin and dalfopristin (Synercid®)
|
Non Formulary
|
|
|
|
Raltegravir (Isentress ®)
|
Non Formulary
|
|
|
|
Ribavirin (Virazole®)
|
Non Formulary
|
|
|
|
Rifampicin (Rifadin®)
|
Non Formulary
|
|
|
|
Rifampicin (Rimactane®)
|
Non Formulary
|
|
|
|
Rifampicin and Isoniazid (Rimactazid® 300)
|
Non Formulary
|
|
|
|
Rifaximin tablets 200mg (Xifaxanta ®)
|
Non Formulary
|
Licenced for traveller's diarrhoea |
|
|
Ritonavir (Norvir®)
|
Non Formulary
|
|
|
|
Ritonavir (Norvir®)
|
Non Formulary
|
|
|
|
Saquinavir (Invirase®)
|
Non Formulary
|
|
|
|
Sodium fusidate (Fucidin®)
|
Non Formulary
|
|
|
|
Sodium Stibogluconate (Pentostam®)
|
Non Formulary
|
|
|
|
Sofosbuvir with velpatasvir and voxilaprevir (Vosevi®)
|
Non Formulary
|
For initiation by Consultant Gastroenterologists only as per NHS England Hepatitis C commissioning policy |
NICE TA507: Sofosbuvir–velpatasvir–voxilaprevir for treating chronic hepatitis C
|
Stavudine (Zerit®)
|
Non Formulary
|
|
|
|
Sulfadiazine
|
Non Formulary
|
|
|
|
Sulfadiazine
|
Non Formulary
|
|
|
|
telithromycin (Ketek®)
|
Non Formulary
|
|
|
|
Tenofovir 245mg, Efavirenz 600mg and Emtricitabine 200mg (Atripla®)
|
Non Formulary
|
|
|
|
Tenofovir and Emtricitabine (Truvada®)
|
Non Formulary
|
|
|
|
Terbinafine (Lamisil®)
|
Non Formulary
|
|
|
|
Tetracycline
|
Non Formulary
|
|
|
|
Tetracycline (Deteclo®)
|
Non Formulary
|
|
|
|
Tinidazole
|
Non Formulary
|
|
|
|
Tinidazole (Fasigyn®)
|
Non Formulary
|
|
|
|
Tipranavir (Aptivus®)
|
Non Formulary
|
|
|
|
Vancomycin (Vancocin®)
|
Non Formulary
|
|
|
|
Zidovudine and Lamivudine (Combivir®)
|
Non Formulary
|
|
|
|
Zidovudine and lamivudine (Combivir®)
|
Non Formulary
|
|
|
|
| |
Key |
|
|
|
|
Cytotoxic Drug
|
|
|
Controlled Drug
|
|
High Cost Medicine
|
|
Cancer Drugs Fund
|
|
NHS England |
|
Homecare |
|
CCG |
|
Traffic Light Status Information
| Status |
Description |
|
"Amber 1" - These are medicines that require significant monitoring and the decision to treat with an AMBER medicine should be made by specialists only |
|
"Amber 2" - These are medicines that require little or no monitoring by the GP, but should only be prescribed in general practice after they have been recommended following specialist referral. |
|
"Red" - Secondary care only |
|
"Double Red" - NOT recommended for prescribing in either primary or secondary care |
|
Traffic light status to be confirmed |
|
May be prescribed in primary and secondary care |
|
|
|
