Formulary Chapter 15: Anaesthesia - Full Chapter
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15.01 |
General anaesthesia |
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15.01 |
Anaesthesia, sedation and resuscitation in dental practice |
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15.01.01 |
Intravenous anaesthetics |
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15.01.01 |
Barbiturates |
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Thiopental Sodium
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Formulary
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injection 500mg
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15.01.01 |
Other intravenous anaesthetics |
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Etomidate (Etomidate-Lipuro®)
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Formulary
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injection (emulsion) 2mg/ml
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Ketamine (Ketalar®)
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Formulary
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Injection 100mg/ml, 200mg/20ml, and 500mg/5ml
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Propofol
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Formulary
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Infusion 1% (1g/100ml and 500mg/50ml)
Injection 1% (200mg/20ml)
Injection 2% (1g/50ml)
Syringe 1% (500mg/50ml)
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15.01.02 |
Inhalational anaesthetics |
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15.01.02 |
Volatile liquid anaesthetics |
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Desflurane (Suprane®)
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Formulary
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Bottle 240ml
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Isoflurane
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Formulary
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Bottle 250ml
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Methoxyflurane inhalation vapour 3ml (Penthrox®)
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Formulary
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For use in A&E only
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Sevoflurane
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Formulary
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Bottle 250ml
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15.01.03 |
Antimuscarinic drugs |
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Atropine Sulphate
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Formulary
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Injection 600mcg/ml
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Atropine Sulphate (minijet® Atropine)
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Formulary
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Pre-filled syringe 500mcg/5ml
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Glycopyrronium Bromide (Glycopyrrolate) (Robinul®)
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Formulary
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Injection 200mcg/ml and 600mcg/3ml
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Hyoscine Hydrobromide
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Formulary
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Injection 400mcg/ml
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15.01.04 |
Sedative and analgesic peri-operative drugs |
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15.01.04.01 |
Benzodiazepines |
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Diazepam
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Formulary
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Tablets 2mg and 5mg
Oral solution 2mg/5ml and 5mg/5ml
Injection (emulsion) 10mg/2ml
Injection (solution) 10mg/2ml
Rectal tubes 2.5mg, 5mg, and 10mg
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Lorazepam
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Formulary
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Tablets 1mg and 2.5mg
Injection 4mg/ml
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Midazolam
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Formulary
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Oral (buccal) liquid 2.5mg/ml
Injection 10mg/2ml, 10mg/5ml, 2mg/2ml, 5mg/5ml, and 50mg/50ml
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Temazepam
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Formulary
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Until 31 May 2015 Temazepam is exempted from the CD prescription writing requirements, but from 1 June 2015, the exemption is being removed, meaning that prescriptions will need to comply fully with the requirements for Schedule 3 controlled drugs.
Tablets 10mg
Oral solution 10mg/5ml
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15.01.04.02 |
Non-opioid analgesics |
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Parecoxib (Dynastat®)
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Restricted
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Restricted to consultants only.
Injection (with solvent) 40mg
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15.01.04.03 |
Opioid analgesics |
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Alfentanil (Rapifen®)
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Formulary
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Injection 1mg/2ml Intensive care injection 5mg/ml
Infusion bags 25mg/50ml (ICU only)
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Fentanyl
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Formulary
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Injection 100mcg/2ml
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Remifentanil (Ultiva®)
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Formulary
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Injection 1mg and 2mg
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15.01.04.04 |
Other drugs for sedation |
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Dexmedetomidine injection 100mg/ml (Dexdor ®)
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Restricted
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To be initiated by Consultants Anaesthetists for ICU patients only
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15.01.05 |
Neuromuscular blocking drugs |
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15.01.05 |
Non-depolarising muscle relaxants |
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Atracurium Besilate
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Formulary
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Injection 25mg/2.5ml, 50mg/5ml, and 250mg/25ml
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Mivacurium Chloride (Mivacron®)
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Formulary
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Injection 10mg/5ml
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Pancuronium Bromide
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Formulary
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Injection 4mg/2ml
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Rocuronium Bromide (Esmeron®)
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Restricted
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For use while vecuronium unavailable
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Vecuronium Bromide (Norcuron®)
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Formulary
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Injection (with WFI) 10mg
**NOTE - due to mannufacturing problems, vecuronium is unlikely to be available before the end of 2013**
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15.01.05 |
Depolarising muscle relaxants |
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Suxamethonium Chloride
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Formulary
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Injection 100mg/2ml
Syringe 100mg/2ml
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15.01.06 |
Drugs for reversal of neuromuscular blockade |
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15.01.06 |
Anticholinesterases |
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Edrophonium Chloride
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Restricted
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CURRENTLY UNAVAILABLE (UNLICENSED PREPARATION PENDING)
Injection 10mg/ml
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Neostigmine Metilsulfate
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Formulary
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Injection 2.5mg/ml
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Neostigmine Metilsulfate with Glycopyrronium (Robinul-Neostigmine®)
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Formulary
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Injection 2.5mg/500mcg/ml
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15.01.06 |
Other drugs for reversal of neuromuscular blockade |
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Sugammadex (Bridion®)
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Restricted
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Sugammadex is restricted to consultants and anaesthetists only.
Injection 200mg/2ml and 500mg/5ml
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15.01.07 |
Antagonists for central and respiratory depression |
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Doxapram Hydrochloride (Dopram®)
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Formulary
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Of limited value in anaesthesia
Injection 100mg/5ml
Infusion 1g in 500ml
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Flumazenil
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Formulary
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Injection 500mcg/5ml
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Naloxone Hydrochloride (Naloxone®)
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Formulary
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Injection 400mcg/ml
Syringe (Minijet) 400mcg/ml
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15.01.08 |
Drugs for malignant hyperthermia |
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Dantrolene Sodium (Dantrium Intravenous®)
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Formulary
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Injection 20mg
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15.01.09 |
Prophylaxis of acid aspiration |
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Hydrocaine gel
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Formulary
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6ml and 11ml
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Bupivacaine and Adrenaline
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Formulary
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Injection bupivacaine 0.25% adrenaline 1:200000
Injection bupivacaine 0.5% adrenaline 1:200000
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Bupivacaine Hydrochloride
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Formulary
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Injection 0.25% and 0.5%
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Bupivacaine Hydrochloride with Glucose (Marcaine Heavy®)
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Formulary
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Injection bupivacaine 20mg glucose 320mg (4ml)
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Bupivacaine with Fentanyl
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Formulary
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Injection bupivacaine 0.1% fentanyl 20mcg (10ml)
Infusion bupivacaine 0.1% fentanyl 1mg (500ml)
Infusion bupivacaine 0.1% fentanyl 500mcg (250ml)
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Levobupivacaine (Chirocaine®)
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Formulary
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Injection 25mg/10ml, 50mg/10ml, and 75mg/10ml
Infusion levobupivacaine 0.1% fentanyl 1mg (500ml)
Infusion levobupivacaine 0.1% fentanyl 500mcg (250ml)
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15.02 |
Lidocaine |
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Lidocaine 2% (minijet®)
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Formulary
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Pre-filled syringe 2%
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Lidocaine 2.5% with Prilocaine 2.5% (EMLA®)
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Formulary
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Cream (premedication pack)
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Lidocaine cream 4% (LMX4®)
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Formulary
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Lidocaine HCL 2% with Chlorhexidine dihydrochloride 0.05% (Cathejell®)
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Formulary
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Syringe (8.5g and 12.5g)
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Lidocaine HCl 2% with Chlorhexidine gluconate 0.25% (Instillagel®)
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Restricted
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Syringe (6ml and 11ml)
For dental use only
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Lidocaine HCl with Adrenaline
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Formulary
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Injection lidocaine 1% adrenaline 1:200000
Injection lidocaine 2% adrenaline 1:200000
Cartridge lidocaine 2% adrenaline 1:80000
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Lidocaine Hydrochloride
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Formulary
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Injection 0.5%
Injection 1% (2ml, 5ml, 10ml, and 20ml)
Injection 2% (2ml, 5ml, and 20ml)
Syringe 4%
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Lidocaine in Glucose
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Formulary
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Infusion 0.2% lidocaine in 5% glucose (500ml)
Infusion 0.4% lidocaine in 5% glucose (500ml)
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Prilocaine Hydrochloride (Citanest®)
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Formulary
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Injection 1%
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15.02 |
Tetracaine |
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Tetracaine (Amethocaine) gel 4% (Ametop®)
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Alternatives
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October 2018 - replaced with lidocaine cream (LMX4)
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15.02 |
Other local anaesthetics |
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Antacid with Oxetacaine
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Restricted
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Last line option for severe chemotherapy induced mucositis.
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Cocaine
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Restricted
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For the use of ENT only.
Solution 10%
Paste 25%
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Ethyl Chloride (Cryogesic® Spray)
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Formulary
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Spray
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Non Formulary Items |
Atracurium Besilate (Tracrium®)

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Non Formulary
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Atropine Sulphate

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Non Formulary
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Syringe 1mg/10ml |
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Benzocaine

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Non Formulary
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Benzocaine 20% Gel (Ultracare® Bubble Gum)

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Non Formulary
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Bupivacaine hydrochloride (Marcain heavy®)

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Non Formulary
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Bupivacaine hydrochloride (Marcain®)

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Non Formulary
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Cistracurium (Nimbex®)

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Non Formulary
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Cocaine with Adrenaline

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Non Formulary
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Dermogesic spray

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Non Formulary
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Etomidate (Hypnomidate®)

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Non Formulary
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Fentanyl (Sublimaze®)

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Non Formulary
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Flumazenil (Anexate®)

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Non Formulary
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Isoflurane (AErrane®)

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Non Formulary
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Ketamine Oral Solution

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Non Formulary
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Ketorolac Trometamol (Toradol®)

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Non Formulary
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Levobupivacaine with Fentanyl

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Non Formulary
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Lidocaine (laryngojet®)

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Non Formulary
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Lidocaine (Xylocaine®)

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Non Formulary
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Lidocaine and chlorhexidine

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Non Formulary
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Lidocaine HCl 5% and Phenylephrine HCl 0.5%

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Non Formulary
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Lidocaine Hydrochloride (Xylocaine®)

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Non Formulary
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Lidocaine Plasters 5% (700mg/medicated plaster) (Versatis®)

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Non Formulary
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For the management of post herpetic neuralgia with allodynia, requests for Versatis may be made via the Prior Approval process |
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Midazolam (Hypnovel®)

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Non Formulary
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Prilocaine Hydrochloride (Prilotekal®)

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Non Formulary
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Prilocaine Hydrochloride with Felypressin (Citanest with Octapressin®)

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Non Formulary
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Procaine Hydrochloride

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Non Formulary
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Propofol (Diprivan®)

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Non Formulary
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Ropivacaine Hydrochloride (Naropin®)

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Non Formulary
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Suxamethonium Chloride (Anectine®)

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Non Formulary
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Key |
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Cytotoxic Drug
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Controlled Drug
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High Cost Medicine
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Cancer Drugs Fund
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NHS England |
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Homecare |
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CCG |
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Traffic Light Status Information
Status |
Description |

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"Amber 1" - These are medicines that require significant monitoring and the decision to treat with an AMBER medicine should be made by specialists only |

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"Amber 2" - These are medicines that require little or no monitoring by the GP, but should only be prescribed in general practice after they have been recommended following specialist referral. |

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"Red" - Secondary care only |

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"Double Red" - NOT recommended for prescribing in either primary or secondary care |

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Traffic light status to be confirmed |

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May be prescribed in primary and secondary care |
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