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 Formulary Chapter 13: Skin - Full Chapter
13.05.03  Expand sub section  Drugs affecting the immune response
Adalimumab (Humira®)
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Restricted Drug Restricted
Red
Injection 40mg/0.8ml

as per NICE TA 146 - for the treatment of adults with psoriasis 
Link  NICE TA 146 - Adalimumab for the treatment of adults with psoriasis
Link  NICE TA392: Adalimumab for treating moderate to severe hidradenitis suppurativa
   
Apremilast tablets (Otezla®)
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Restricted Drug Restricted
Red
High Cost Medicine
Treatment initiation pack: 4 x 10mg, 4 x 20mg, 19 x 30mg tablets
Maintenance pack: 30mg tablets 
Link  NICE TA419: Apremilast for treating moderate to severe plaque psoriasis
Link  NICE TA433: Apremilast for treating active psoriatic arthritis
   
Ciclosporin (Neoral®)
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Formulary
Amber 1

Capsules 10mg, 25mg, 50mg, and 100mg
Solution 100mg/ml

 
   
Ciclosporin  (Sandimmun®)
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Formulary Infusion 5% (50mg/ml) 
   
Infliximab (Remicade®)
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Restricted Drug Restricted
Red
100mg vial

Indicated as per NICE TA146 for psoriasis 
Link  NICE TA134- Infliximab for the treatment of adults with psoriasis
   
Ixekizumab injection 80mg (Taltz®)
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Restricted Drug Restricted
High Cost Medicine
 
Link  NICE TA442: Ixekizumab for treating moderate to severe plaque psoriasis
Link  NICE TA537: Ixekizumab for treating active psoriatic arthritis after inadequate response to DMARDs
   
Methotrexate tablets 2.5mg
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Formulary
Amber 1
For dermatology indications. For other indications, see relevant chapters. 
   
Pimecrolimus Cream 1% (Elidel®)
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Restricted Drug Restricted Pimecrolimus is restricted to dermatology use only.

Cream (30g) 
   
Sarilumab (Kevzara®)
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Restricted Drug Restricted
Red
 
Link  NICE TA485: Sarilumab for moderate to severe rheumatoid arthritis
   
Secukinumab (Cosentyx®)
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Restricted Drug Restricted
Red
Dermatologists only 
Link  NICE TA350: Secukinumab for treating moderate to severe plaque psoriasis
Link  NICE TA407: Secukinumab for active ankylosing spondylitis after treatment with non-steroidal anti-inflammatory drugs or TNF-alpha inhibitors
Link  NICE TA445: Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDs
   
Tacrolimus Ointment 0.03% (Protopic®)
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Restricted Drug Restricted
Amber 2

Tacrolimus Ointment is restricted to dermatology use only and ordered in on request only.

Ointment (30g)

 
Link  NICE TA82: Tacrolimus and pimecrolimus for atopic eczema
   
Tacrolimus Ointment 0.1% (Protopic®)
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Restricted Drug Restricted
Amber 2

Tacrolimus Ointment is restricted to dermatology use only.

Ointment (30g)

 
Link  NICE TA82: Tacrolimus and pimecrolimus for atopic eczema
   
Tildrakizumab (Ilumetri®)
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Restricted Drug Restricted
CCG
BlueTeq
 
Link  NICE TA575: Tildrakizumab for treating moderate to severe plaque psoriasis
   
Ustekinumab (Stelara)
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Restricted Drug Restricted
Red

https://www.nice.org.uk/guidance/ta633

 
Link  NICE TA180: Ustekinumab for the treatment of adults with moderate to severe psoriasis
Link  NICE TA313: Superceded by TA340
Link  NICE TA340: Ustekinumab for treating active psoriatic arthritis (rapid review of technology appraisal guidance 313)
Link  NICE TA456: Ustekinumab for moderately to severely active Crohn’s disease after previous treatment
Link  NICE TA633L Ustekinumab for treating moderately to severely active ulcerative colitis
   
13.05.03.01  Expand sub section  Cytokine modulators (biologic therapies) - eczema
13.05.03.02  Expand sub section  Cytokine modulators (biologic therapies) - psoriasis
 ....
 Non Formulary Items
Efalizumab  (Raptiva®)

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Non Formulary
Red
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber 1

"Amber 1" - These are medicines that require significant monitoring and the decision to treat with an AMBER medicine should be made by specialists only  

Amber 2

"Amber 2" - These are medicines that require little or no monitoring by the GP, but should only be prescribed in general practice after they have been recommended following specialist referral.  

Red

"Red" - Secondary care only  

RedRed

"Double Red" - NOT recommended for prescribing in either primary or secondary care  

Grey

Traffic light status to be confirmed  

Green

May be prescribed in primary and secondary care  

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